Introduction
In veterinary care, Amodis Vet Bolus is a key antimicrobial solution used to combat a variety of infections in animals. The bolus contains Metronidazole, an effective antimicrobial agent against protozoa and anaerobic bacteria. For common conditions like trichomoniasis in livestock or more complex intestinal issues such as giardiasis, Amodis-Vet® provides a fast and reliable treatment option.
This article explores the uses, benefits, and mechanism of action of Metronidazole and the appropriate dosage for animals like dogs. It provides insights into Metronidazole antibiotic pricing in regions like the Philippines.
What is Amodis Vet Bolus?
Amodis-Vet® is a veterinary bolus formulated with Metronidazole, widely known for its antimicrobial properties. It primarily treats anaerobic bacterial infections and protozoal diseases in large animals and poultry.
Key Features
- Delivers a high dose of Metronidazole in an easily administrable form.
- Targets hard-to-reach infections in the gastrointestinal tract and reproductive system.
- Disrupts the DNA of microorganisms, effectively killing them or preventing their replication.
Amodis Vet and Its Mechanism of Action
Metronidazole works as both an antibiotic and an antiprotozoal agent.
Mechanism of Action
- Disruption of DNA: Reduces the nitro group in microorganisms, forming highly reactive intermediates.
- Inhibition of Nucleic Acid Synthesis: Leads to bacterial cell death.
- Targeted Action: Effective against anaerobic bacteria thriving in low-oxygen environments like the intestines and reproductive organs.
Conditions Treated by Amodis Vet
- Metritis, Vaginitis, and Endometritis.
- Intestinal infections such as giardiasis.
- Protozoal diseases, including trichomoniasis.
Indications for Use in Animals
Amodis Vet is ideal for treating many infections in large animals and poultry.
Standard Conditions of Amodis Vet
Large Animals
- Metritis and Endometritis: Infections of the uterus, common in cattle post-birth.
- Vaginitis: Inflammation of the vagina in livestock and pets.
- Amoebic Dysentery and Calf Scour: Intestinal infections in young livestock.
- Post-Surgical Infections: Prevents and treats infections after colon surgery.
Poultry
- Histomoniasis: Parasitic liver disease.
- Trichomoniasis and Giardiasis: Protozoal infections affecting the digestive and reproductive systems.
Dosage & Administration of Amodis Vet
The correct dosage ensures effectiveness while minimizing potential side effects.
For Large Animals
- Oral Administration: 40–50 mg/kg body weight for 5–7 days.
- Intra-Uterine Administration: 4 boli per 100 kg body weight for uterine infections.
For Poultry
- 1 bolus per 3–6 litres of drinking water for 4–6 days.
Metronidazole Dosage for Dogs
- Typical Dosage: 5–10 mg/kg body weight orally every 12 hours for 5–7 days.
- Always consult a veterinarian for personalized dosing instructions.
Side Effects of Amodis-Vet
Amodis Vet is generally safe, but side effects may occur when used as directed.
Common Side Effects of Amodis Vet
- Gastrointestinal Upset: Vomiting, diarrhoea, and salivation.
- Appetite Loss: Reduced food intake during treatment.
- Neurological Symptoms: Rarely, ataxia or disorientation.
When to Seek Veterinary Advice
If side effects persist, consult a veterinarian immediately.
Precautions and Contraindications Of Amodis Vet
- Pregnancy: Avoid use during the first trimester.
- Lactation: Not recommended for lactating animals.
- Young Animals: Not suitable for puppies or kittens.
- Liver or Kidney Disease: Use cautiously in animals with these conditions.
Drug Interactions
Certain drugs may interact with Metronidazole, requiring dose adjustments.
Common Interactions
- Warfarin: Increases the risk of bleeding.
- Cimetidine: Affects liver metabolism of Metronidazole.
- Phenobarbital and Phenytoin: Accelerate Metronidazole metabolism.
Price of Metronidazole in the Philippines
The cost of Metronidazole tablets in the Philippines varies based on formulation and supplier. Specialized veterinary products like Amodis-Vet® Bolus may be priced higher.
For accurate pricing, consult local veterinary clinics or distributors.
Why Choose Amodis Vet Bolus?
Key Advantages
- Rapid Absorption: Fast therapeutic effects.
- Anti-inflammatory Properties: Effective against IBD and inflammatory bowel disorders.
- Compatibility: Can be combined with penicillin, aminoglycosides, and cephalosporins.
Conclusion
Amodis Vet Bolus is a versatile and effective solution for treating various infections in animals and poultry. Addressing conditions like trichomoniasis, giardiasis, and IBD ensures better animal health and well-being.
FAQs
What is the mechanism of action of Metronidazole?
Metronidazole inhibits DNA synthesis in bacteria and protozoa, leading to their destruction.
Is Metronidazole safe for dogs?
Yes, when administered at the correct dosage (5–10 mg/kg body weight).
Can Metronidazole be used with other antibiotics?
Yes, it is compatible with antibiotics like penicillin and cephalosporins.
How much does Metronidazole cost in the Philippines?
Depending on the supplier.
Can Amodis-Vet® be used in pregnant animals?
No, it should be avoided during pregnancy, especially in the first trimester.
What should I do if my dog experiences side effects?
Consult a veterinarian immediately if side effects like vomiting or appetite loss occur.
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